Opportunity Information: Apply for COCLI 2021

The Combating Overdose through Community-Level Intervention (COCLI) grant opportunity is a one-year federal cooperative agreement run by the Office of National Drug Control Policy (ONDCP) to help communities respond to the accelerating overdose crisis, which worsened during the COVID-19 pandemic. The program is framed around the sharp rise in overdose deaths nationwide, including increasing deaths involving opioids, synthetic opioids like fentanyl, and stimulants such as methamphetamine. The core idea is to strengthen and coordinate local overdose response efforts in the parts of the country facing the highest rates of fatal and non-fatal overdoses, while also building better collaboration between public health and public safety partners.

ONDCP expects to make a single award, meaning one lead organization will be selected to carry out the initiative at a national or multi-community scale. The award is structured as a cooperative agreement (rather than a standard grant), which signals close federal involvement and ongoing coordination with ONDCP. The project is expected to begin around September 2021 and run for 12 months (through approximately August 2022), with total funding up to $3,000,000. Because this is cooperative, the funded organization should anticipate active partnership not only with ONDCP but also alignment with related efforts led by the Centers for Disease Control and Prevention (CDC), especially where data, response strategies, and evaluation methods intersect.

The work ONDCP is paying for has several connected parts. First, the recipient must research and analyze existing community-level overdose interventions and identify evidence-based strategies that have demonstrated impact, including approaches that explicitly advance equity. Second, using those proven approaches, the recipient must implement or strengthen overdose reduction programs in high-burden regions. A key preference is given to proposals that push resources down to the local level through subawards, with priority for plans that fund at least eight communities. Third, the recipient must support evaluation of the implemented or enhanced interventions to determine how well they reduce overdose deaths and other harms related to substance misuse, again with a focus on places experiencing the highest burden. Alongside the programmatic work, the recipient is expected to promote and structure collaboration between public health agencies and law enforcement, reflecting ONDCPs emphasis that coordinated public safety and public health action is essential for a comprehensive overdose response. Finally, the recipient must provide technical assistance to help subaward communities implement programs effectively, evaluate outcomes, and meet reporting requirements.

A defining feature of COCLI is that it is meant to organize and strengthen what can otherwise be fragmented local and state overdose response efforts. The opportunity explicitly anticipates partnership with federally designated High Intensity Drug Trafficking Area (HIDTA) programs, which are funded by ONDCP and already work with CDC through the Overdose Response Strategy initiative. In practical terms, applicants are expected to show they can operate in complex multi-stakeholder environments, bring public health and law enforcement to the same table, and build a consistent approach to identifying overdose trends, selecting interventions, and measuring results across multiple communities. Because the program was designed during the pandemic, ONDCP also notes that special consideration will be given to innovative strategies that expand reach while still following CDC safety guidance.

The legal authority for the funding comes from the SUPPORT for Patients and Communities Act and the Consolidated Appropriations Act, 2021. Administrative and compliance expectations follow the Uniform Guidance (2 C.F.R. Part 200, as adopted by ONDCP), which means the awardee must maintain strong financial management and internal controls, monitor compliance, address any noncompliance promptly (including audit issues), and protect sensitive information such as personally identifiable data consistent with privacy and confidentiality requirements. In short, ONDCP is looking for an organization that can manage federal funds responsibly while running a fast-moving, evidence-driven initiative that includes subawards, technical assistance, and evaluation.

Eligibility is aimed at capable non-federal entities, with encouragement directed particularly to nonprofit organizations that have deep expertise in developing, strengthening, and coordinating evidence-based overdose reduction programs. Eligible applicant types listed include public and state-controlled institutions of higher education and 501(c)(3) nonprofits (other than institutions of higher education). Importantly, there is no cost sharing or matching requirement, which lowers the barrier for qualified organizations that can demonstrate expertise, partnerships, and readiness to deploy funds quickly. The opportunity was posted under Funding Opportunity Number COCLI 2021 (CFDA 95.007), with an original closing date of August 13, 2021, and it anticipates just one award at the $3,000,000 ceiling.

  • The Office of National Drug Control Policy in the health sector is offering a public funding opportunity titled "Combating Overdose through Community-Level Intervention" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 95.007.
  • This funding opportunity was created on Aug 05, 2021.
  • Applicants must submit their applications by Aug 13, 2021. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $3,000,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Public and State controlled institutions of higher education, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
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