Opportunity Information: Apply for PAR 19 285
Infrastructure Development Training Programs for Critical HIV Research at Low-and Middle-Income Country Institutions (PAR 19-285) is a Fogarty International Center (FIC), National Institutes of Health (NIH) grant opportunity designed to strengthen HIV research capacity in low- and middle-income countries (LMICs). The central aim is not to fund HIV clinical trials, but to build the underlying institutional systems and skilled workforce needed for high-quality, compliant, and sustainable HIV research in settings where the epidemic is evolving and local research leadership is essential.
The program specifically promotes collaborative applications that link U.S. institutions with LMIC institutions. These partnerships are meant to deliver structured training that improves the technical skills and the administrative and financial management capabilities required to run a strong research enterprise. Rather than focusing on training individual scientists in a narrow discipline alone, this opportunity emphasizes research infrastructure functions that make research possible at scale and at high standards. The intent is to help LMIC institutions develop reliable internal processes, oversight, and services so they can conduct rigorous HIV research and also serve as hubs that can train others in their own countries and across other LMICs.
Applications are expected to concentrate on building expertise in one of six research infrastructure functions that NIH identifies as critical to a successful research environment. These functions include: (1) research administration and management, which covers the operational backbone of grants and research programs; (2) research integrity oversight, which supports responsible conduct of research and helps prevent misconduct and poor research practices; (3) ethical review of research for the protection of human subjects, strengthening Institutional Review Boards or equivalent ethics committees and their procedures; (4) laboratory animal welfare oversight, ensuring humane care and use of animals in research and alignment with accepted welfare standards; (5) health sciences library and information services, improving access to scientific literature, knowledge management, and research support resources; and (6) information and communications technology (ICT) systems for research, which can include data systems, connectivity, secure storage, and other enabling digital infrastructure and support.
A key theme of the opportunity is sustainability and broader impact. These training programs are positioned as a way to maximize prior investments in LMIC research capacity and to extend the benefits beyond a single institution. In practice, that means creating training approaches, materials, and local expertise that can be reused and shared, enabling LMIC institutions to provide more accessible research infrastructure training to additional organizations in-country and regionally. The overall result NIH is aiming for is stronger institutional capability to design, oversee, manage, and support HIV research that meets international expectations for quality, ethics, compliance, and accountability.
The funding mechanism is a grant under an education and health-related activity category, with CFDA numbers 93.279 and 93.989. Eligible applicants include a wide range of organizations such as public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations (both 501(c)(3) and non-501(c)(3)), and other eligible entities. The opportunity explicitly notes additional eligible applicant types that often play major roles in capacity-building and workforce development, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Tribally Controlled Colleges and Universities (TCCUs), and non-U.S. entities (foreign organizations), reflecting the program’s emphasis on inclusive partnerships and direct engagement with LMIC institutions.
Administratively, the opportunity was created on May 14, 2019, and it listed an original closing date of August 20, 2021. It is identified as “G11 Clinical Trials Not Allowed,” signaling that the funded activities should focus on training and infrastructure-development functions rather than conducting clinical trials. Overall, this FOA is best understood as an institutional capacity and systems-strengthening program for HIV research: it targets the less visible, but essential, components that determine whether research programs can operate efficiently, ethically, and sustainably in LMIC settings.Apply for PAR 19 285
- The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Infrastructure Development Training Programs for Critical HIV Research at Low-and Middle-Income Country Institutions (G11 Clinical Trials Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279, 93.989.
- This funding opportunity was created on 2019-05-14.
- Applicants must submit their applications by 2021-08-20. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Public and State controlled institutions of higher education, Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, Others.
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Frequently Asked Questions (FAQs)
What is PAR 19-285?
PAR 19-285 is the "Infrastructure Development Training Programs for Critical HIV Research at Low-and Middle-Income Country Institutions" funding opportunity from the Fogarty International Center (FIC) at the National Institutes of Health (NIH). It supports training programs that strengthen HIV research capacity in low- and middle-income countries (LMICs).
What is the main goal of this grant opportunity?
The central goal is to build the institutional systems and skilled workforce needed for high-quality, compliant, and sustainable HIV research in LMIC institutions. The focus is on strengthening the research enterprise so institutions can reliably design, manage, oversee, and support rigorous HIV research.
Does this program fund HIV clinical trials?
No. The opportunity is identified as "G11 Clinical Trials Not Allowed." It is designed to support training and infrastructure-development functions rather than the conduct of HIV clinical trials.
Who is the sponsoring NIH component?
The program is sponsored by the Fogarty International Center (FIC), National Institutes of Health (NIH).
Why does the opportunity emphasize institutional systems rather than training only individual researchers?
The program emphasizes research infrastructure functions that enable research to operate at scale and at high standards. The intent is to strengthen the less visible but essential capabilities (administrative, ethical, compliance, information, and systems support) that determine whether an institution can run a strong, sustainable research enterprise.
What kinds of partnerships are encouraged?
The opportunity specifically promotes collaborative applications that link U.S. institutions with LMIC institutions. These partnerships are intended to deliver structured training that improves both technical skills and the administrative and financial management capabilities needed for a strong research environment.
What is meant by "research infrastructure functions" in this FOA?
In this context, research infrastructure functions are the institutional services, oversight processes, and operational systems that make high-quality research possible, compliant, and sustainable. They include areas like research administration, ethics review, integrity oversight, ICT systems, and other core supports.
How many research infrastructure functions does NIH identify as critical under this opportunity?
NIH identifies six critical research infrastructure functions for this funding opportunity.
What are the six research infrastructure functions applicants can focus on?
The six functions are:
- Research administration and management
- Research integrity oversight
- Ethical review of research for the protection of human subjects
- Laboratory animal welfare oversight
- Health sciences library and information services
- Information and communications technology (ICT) systems for research
What does "research administration and management" include?
It covers the operational backbone of grants and research programs, supporting the day-to-day running of research activities and institutional grant management.
What does "research integrity oversight" focus on?
It supports responsible conduct of research and helps prevent misconduct and poor research practices by strengthening integrity-related oversight at institutions.
What does "ethical review of research for the protection of human subjects" refer to?
It refers to strengthening Institutional Review Boards (IRBs) or equivalent ethics committees and improving their procedures to ensure research involving people meets appropriate protections and ethical standards.
What does "laboratory animal welfare oversight" mean in this program?
It focuses on ensuring humane care and use of animals in research and alignment with accepted animal welfare standards through strengthened oversight systems.
What is included under "health sciences library and information services"?
This area focuses on improving access to scientific literature and strengthening knowledge management and research support resources that help researchers and institutions find, use, and manage scientific information.
What does "ICT systems for research" cover?
ICT can include data systems, connectivity, secure storage, and other enabling digital infrastructure and support needed for modern research operations.
Do applications need to address all six functions?
No. Applications are expected to concentrate on building expertise in one of the six research infrastructure functions identified as critical.
What is the program trying to achieve in terms of sustainability?
Sustainability is a key theme. The program aims to help LMIC institutions develop reliable internal processes, oversight, and services that continue beyond the grant period and support ongoing high-quality HIV research.
How is broader impact beyond a single institution expected to happen?
The opportunity emphasizes creating training approaches, materials, and local expertise that can be reused and shared. LMIC institutions are encouraged to become hubs that can train others within their own countries and across other LMICs.
How does this opportunity relate to previous investments in LMIC research capacity?
These training programs are positioned to maximize prior investments in LMIC research capacity by strengthening the institutional systems that allow earlier scientific and workforce investments to translate into durable research capability.
What category of activity does the funding mechanism fall under?
The funding mechanism is a grant under an education and health-related activity category.
What are the CFDA numbers associated with this opportunity?
The CFDA numbers listed are 93.279 and 93.989.
Who is eligible to apply?
Eligible applicants include a wide range of organizations, including public and state-controlled institutions of higher education, private institutions of higher education, and nonprofit organizations (both 501(c)(3) and non-501(c)(3)), along with other eligible entities described in the opportunity.
Are non-U.S. (foreign) organizations eligible?
Yes. The opportunity explicitly includes non-U.S. entities (foreign organizations), consistent with its emphasis on direct engagement with LMIC institutions.
Are minority-serving institutions specifically mentioned as eligible applicants?
Yes. The opportunity explicitly notes additional eligible applicant types, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), and Tribally Controlled Colleges and Universities (TCCUs).
When was this funding opportunity created?
The opportunity was created on May 14, 2019.
What was the original closing date listed for this opportunity?
The original closing date listed was August 20, 2021.
What does "G11 Clinical Trials Not Allowed" signal to applicants?
It signals that funded activities should focus on training and infrastructure-development functions that strengthen research systems, rather than conducting clinical trials.
What is the overall outcome NIH is aiming for with this program?
NIH is aiming for stronger LMIC institutional capability to design, oversee, manage, and support HIV research that meets international expectations for quality, ethics, compliance, and accountability.
How should this FOA be understood at a high level?
It is best understood as an institutional capacity and systems-strengthening program for HIV research in LMIC settings, targeting the operational, oversight, and enabling functions that make rigorous research possible and sustainable.
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| Leveraging Big Data Science to Elucidate the Mechanisms of HIV Activity and Interaction with Substance Use Disorder (R21 - Clinical Trials Not Allowed) Apply for RFA DA 20 009 Funding Number: RFA DA 20 009 Agency: National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| Leveraging Big Data Science to Elucidate the Mechanisms of HIV Activity and Interaction with Substance Use Disorder (R01 - Clinical Trials Not Allowed) Apply for RFA DA 20 008 Funding Number: RFA DA 20 008 Agency: National Institutes of Health Category: Education, Health Funding Amount: $350,000 |
| Novel Technology Tools to Facilitate Research Using Next Generation Patient-derived Cancer Models (U01 Clinical Trial Not Allowed) Apply for RFA CA 19 055 Funding Number: RFA CA 19 055 Agency: National Institutes of Health Category: Education, Health Funding Amount: $700,000 |
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| Behavioral Science Track Award for Rapid Transition (B/Start)(R03 Clinical Trial Optional) Apply for PAR 19 310 Funding Number: PAR 19 310 Agency: National Institutes of Health Category: Education, Health Funding Amount: $75,000 |
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