Opportunity Information: Apply for PA 24 182
The Mentored Clinical Scientist Research Career Development Award (Parent K08, Independent Clinical Trial Not Allowed) is an NIH career development grant designed to help clinically trained professionals become independent investigators in biomedical, behavioral, and translational research. Its central goal is workforce development: giving people with clinical doctoral degrees the structured mentorship, research training, and dedicated protected time needed to build a strong research trajectory that addresses U.S. health-related research priorities. In practical terms, the K08 supports an intensive, supervised period where the award recipient deepens research skills, generates publishable results, and positions themselves to compete for future independent NIH funding.
This opportunity is issued by the National Institutes of Health (NIH) under Funding Opportunity Number PA 24-182 and uses the grant funding instrument. It sits within a broad set of health and social-service related activity categories and is associated with multiple CFDA (Assistance Listing) numbers, reflecting that many NIH Institutes and Centers can use this parent announcement to support mentored clinician-scientists aligned with their missions. The listing emphasizes that the program is part of a long-standing NIH commitment to clinician-scientist development, especially for individuals who need time carved out from clinical responsibilities to focus on research and career development under the guidance of experienced mentors.
A key limitation is embedded in the title: independent clinical trials are not allowed. That means the award is not intended for applicants proposing to lead their own stand-alone clinical trial as the primary project. While clinical and translational research may be appropriate, applicants generally need to design a research plan that does not place them in the role of independently directing a clinical trial. (NIH often distinguishes between leading an independent trial versus working on research that may involve human participants or contributing to a larger trial under a mentor; the exact boundaries depend on NIH definitions and the specific application details, but the main takeaway is that proposing to independently run a clinical trial would not fit this announcement.)
Eligibility to apply as the applicant organization is broad and spans many U.S.-based entity types. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; public housing authorities/Indian housing authorities; Native American tribal organizations that are not federally recognized tribal governments; nonprofits with and without 501(c)(3) status (excluding institutions of higher education in those nonprofit categories); for-profit organizations (other than small businesses); small businesses; and other eligible organizations. The announcement also explicitly calls out additional eligible applicant types such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal government agencies, regional organizations, Indian/Native American Tribal Governments other than federally recognized, and U.S. territories or possessions.
At the same time, the geographic eligibility rules are strict for applicant organizations: non-domestic (non-U.S.) entities (foreign organizations) are not eligible to apply, and non-domestic components of U.S. organizations are also not eligible to apply. However, foreign components are allowed as defined by the NIH Grants Policy Statement, meaning a U.S. applicant organization can include certain foreign collaborations or elements when they meet NIH’s definition and requirements for a foreign component, even though the primary applicant organization itself must be domestic.
From an administrative standpoint, the opportunity was created on April 24, 2024, and lists an original closing date of May 7, 2027. The provided data do not specify an award ceiling or expected number of awards in the fields shown, which is common for parent NIH announcements because actual budgets, paylines, and award counts can vary by NIH Institute/Center, fiscal year, and the applicant’s proposed scope. Overall, the K08 is best understood as a mentored, protected-time pathway for clinically trained researchers to build the skills, publications, preliminary data, and mentorship network needed to transition into independent, sustained research careers that contribute to national health needs, while avoiding proposals centered on independently led clinical trials under this specific announcement.Apply for PA 24 182
- The National Institutes of Health in the education, environment, food and nutrition, health, income security and social services sector is offering a public funding opportunity titled "Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.172, 93.173, 93.213, 93.233, 93.242, 93.273, 93.279, 93.286, 93.307, 93.310, 93.313, 93.398, 93.837, 93.838, 93.839, 93.840, 93.846, 93.847, 93.853, 93.855, 93.859, 93.865, 93.866, 93.867, 93.879.
- This funding opportunity was created on 2024-04-24.
- Applicants must submit their applications by 2027-05-07.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs): Mentored Clinical Scientist Research Career Development Award (Parent K08, Independent Clinical Trial Not Allowed) - PA 24-182
What is the Mentored Clinical Scientist Research Career Development Award (Parent K08)?
The Mentored Clinical Scientist Research Career Development Award (Parent K08) is an NIH career development grant designed to help clinically trained professionals develop into independent investigators in biomedical, behavioral, and translational research. It supports a structured, mentored period of research training and career development with dedicated protected time to strengthen a clinician-scientist's long-term research trajectory.
What is the main purpose of this K08 opportunity?
The central goal is workforce development. The K08 aims to provide clinically trained researchers with mentorship, research training, and protected time so they can produce publishable results, deepen research skills, and become competitive for future independent NIH research funding.
Who is this award intended to support?
This award is intended for clinically trained professionals with clinical doctoral degrees who need a mentored, intensive research and career development period to transition toward independence as investigators in areas aligned with U.S. health-related research priorities.
What kind of research does the K08 support?
The K08 supports mentored research and career development in biomedical, behavioral, and translational research. The emphasis is on building research skills and a strong research trajectory during a supervised period, typically including generation of publishable findings and foundational work that positions the awardee for later independent funding.
What does "Independent Clinical Trial Not Allowed" mean?
It means the award is not intended for applicants proposing to lead their own stand-alone clinical trial as the primary project. In general, an application that proposes the candidate will independently direct a clinical trial would not fit this announcement.
Does the "clinical trial not allowed" restriction mean human participants research is always prohibited?
Not necessarily. The information provided indicates that clinical and translational research may be appropriate, and NIH often distinguishes between independently leading a trial versus contributing to research that may involve human participants or being part of a larger trial under a mentor. The key takeaway from the announcement description is that proposing to independently run a clinical trial would not fit this opportunity.
What is the funding opportunity number for this program?
The NIH Funding Opportunity Number (FON) is PA 24-182.
Which federal agency issues this opportunity?
This opportunity is issued by the National Institutes of Health (NIH).
What funding instrument is used for this opportunity?
The opportunity uses the grant funding instrument.
Is this a single-institute program or can multiple NIH Institutes and Centers use it?
It is associated with multiple CFDA (Assistance Listing) numbers, reflecting that many NIH Institutes and Centers can use this parent announcement to support mentored clinician-scientists aligned with their missions.
What types of applicant organizations are eligible to apply?
Eligible applicant organizations include a broad range of U.S.-based entities, including:
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and state-controlled institutions of higher education
- Private institutions of higher education
- Federally recognized Native American tribal governments
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than federally recognized tribal governments)
- Nonprofits with 501(c)(3) status (excluding institutions of higher education under the nonprofit category listing)
- Nonprofits without 501(c)(3) status (excluding institutions of higher education under the nonprofit category listing)
- For-profit organizations (other than small businesses)
- Small businesses
- Other eligible organizations
Are specific institution types explicitly called out as eligible?
Yes. The announcement explicitly calls out additional eligible applicant types such as:
- Alaska Native and Native Hawaiian Serving Institutions
- Asian American Native American Pacific Islander Serving Institutions (AANAPISIs)
- Hispanic-serving Institutions
- Historically Black Colleges and Universities (HBCUs)
- Tribally Controlled Colleges and Universities (TCCUs)
- Faith-based or community-based organizations
- Eligible federal government agencies
- Regional organizations
- Indian/Native American Tribal Governments other than federally recognized
- U.S. territories or possessions
Are foreign (non-U.S.) organizations eligible to apply as the applicant?
No. Non-domestic (non-U.S.) entities (foreign organizations) are not eligible to apply as the applicant organization.
Are non-domestic components of U.S. organizations eligible to apply?
No. Non-domestic components of U.S. organizations are also not eligible to apply as the applicant organization.
Are foreign components allowed at all under this opportunity?
Yes. Foreign components are allowed as defined by the NIH Grants Policy Statement. This means a U.S. applicant organization can include certain foreign collaborations or elements when they meet NIH's definition and requirements for a foreign component, even though the applicant organization itself must be domestic.
When was this funding opportunity created?
The opportunity was created on April 24, 2024.
What is the original closing date for this opportunity?
The opportunity lists an original closing date of May 7, 2027.
Does the provided information specify an award ceiling?
No. The provided data do not specify an award ceiling in the fields shown. This is described as common for parent NIH announcements because budgets can vary by NIH Institute/Center, fiscal year, and the proposed scope.
Does the provided information state the expected number of awards?
No. The fields shown do not specify an expected number of awards, which is noted as common for NIH parent announcements due to variation across Institutes/Centers, years, and application scope.
How should applicants think about the K08 in practical terms?
In practical terms, the K08 supports an intensive, supervised period where the award recipient builds research capabilities, produces publishable results, develops preliminary data, and strengthens a mentorship and training structure intended to support a transition to independent, sustained research funding and leadership.
What is the overarching theme emphasized in this announcement?
The announcement emphasizes NIH's long-standing commitment to clinician-scientist development, especially for individuals who need time carved out from clinical responsibilities to focus on research and career development under experienced mentorship.
What is the main proposal risk highlighted by the announcement description?
The main risk highlighted is proposing an independently led clinical trial as the primary project. Since independent clinical trials are not allowed under this opportunity, an application centered on leading a stand-alone clinical trial would be considered a poor fit based on the information provided.
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Applicants also applied for:
Applicants who have applied for this opportunity (PA 24 182) also looked into and applied for these:
| Funding Opportunity |
|---|
| NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Required) Apply for PA 24 193 Funding Number: PA 24 193 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed) Apply for PA 24 194 Funding Number: PA 24 194 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Small Business Transition Grant for New Entrepreneurs (R43/R44 Clinical Trial Not Allowed) Apply for PAR 24 131 Funding Number: PAR 24 131 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed) Apply for PAR 24 152 Funding Number: PAR 24 152 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $375,000 |
| PHS 2024-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed) Apply for PA 24 247 Funding Number: PA 24 247 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| PHS 2024-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed) Apply for PA 24 245 Funding Number: PA 24 245 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| PHS 2024-2 Omnibus Solicitation of the NIH and CDC for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required) Apply for PA 24 246 Funding Number: PA 24 246 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Change of Recipient Organization (Type 7 Parent Clinical Trial Optional) Apply for PA 24 254 Funding Number: PA 24 254 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed) Apply for RFA OD 24 011 Funding Number: RFA OD 24 011 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Building Sustainable Software Tools for Open Science (R03 Clinical Trial Not Allowed) Apply for RFA OD 24 010 Funding Number: RFA OD 24 010 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Postdoctoral Career Transition Award to Promote Diversity (K99/R00 - Independent Clinical Trial Required) Apply for PAR 24 226 Funding Number: PAR 24 226 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Postdoctoral Career Transition Award to Promote Diversity (K99/R00 Independent Clinical Trial Not Allowed) Apply for PAR 24 225 Funding Number: PAR 24 225 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Limited Competition: Knockout Mouse Phenotyping Project Database (UM1) Apply for RFA RM 15 016 Funding Number: RFA RM 15 016 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Limited Competition: Knockout Mouse Production and Phenotyping Project (UM1) Apply for RFA RM 15 017 Funding Number: RFA RM 15 017 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Administrative Supplements to Promote Diversity in Research and Development Small Businesses SBIR/STTR (Admin Supp Clinical Trial Not Allowed) Apply for PA 24 255 Funding Number: PA 24 255 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Innovation Corps (I-Corps) at NIH Program for NIH and CDC Translational Research (Admin Supp Clinical Trial NOT Allowed) Apply for PA 25 212 Funding Number: PA 25 212 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Dissemination and Implementation Research in Health (R01 Clinical Trial Optional) Apply for PAR 25 144 Funding Number: PAR 25 144 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed) Apply for PAR 25 134 Funding Number: PAR 25 134 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $375,000 |
| NIH Research Project Grant (Parent R01 Clinical Trial Required) Apply for PA 25 305 Funding Number: PA 25 305 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed) Apply for PA 25 301 Funding Number: PA 25 301 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
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